Carotid Artery Plaque, Thrombus Formation, and Stroke Risk

The neovascularization within carotid artery plaques, the formation of floating thrombi, and the resulting ulcers from plaque rupture are intrinsically linked in a dangerous chain reaction. This process ultimately contributes to stroke risk. Here's how:

• Neovascularization: New blood vessels form within the carotid artery plaque, making it unstable.
• Thrombus Formation: These fragile blood vessels are prone to rupture, leading to the formation of blood clots known as thrombi.
• Plaque Rupture and Ulcers: As the plaque weakens, it can rupture, forming ulcers and further increasing the risk of thrombus formation.
• Stroke: When these floating thrombi detach, they can travel to the brain, blocking blood flow and causing a stroke.

Understanding this chain reaction highlights the critical role of early detection and management of carotid artery disease in preventing stroke.