Layer V Pyramidal Neuron Dendritic Spine Distribution and Inputs: A Focus on Basal Dendrites

For instance, layer V pyramidal neurons exhibit numerous dendritic spines, with a higher concentration found on their basal dendrites compared to their apical dendrites6. Studies in rodents have revealed that neighboring neurons7 and layer II/III pyramidal neurons provide inputs to the basal dendrites of these large layer V pyramidal neurons.