Plasma Exosome miRNA Expression Profiles Differentiate Alzheimer's Disease Patients from Healthy Controls

Compared to a healthy volunteer group, significant alterations were observed in the levels of miR-223, miR-212, and miRNA-132 in plasma exosomes of AD patients. These changes were found to be statistically significant, suggesting that these miRNAs may serve as potential biomarkers for AD diagnosis and monitoring. Furthermore, the study provides valuable insights into the role of miRNAs in the pathogenesis of AD.