Synthesis and Optimization of Ce-UIO-66 Based SERS Substrates for Enhanced Raman Spectroscopy

The final Ce-UIO-66 powder was dispersed in an ethanol solution with a concentration of 1 mg/mL. The dispersed solution was mixed with prepared Ag@Au solutions at volume ratios of 1:1, 1:2, and 1:3, respectively. The mixture was then vigorously mixed on a high-speed vortex for 5 minutes and incubated at room temperature for 1.5 hours. Finally, the prepared SERS substrates for Raman detection were washed repeatedly with deionized water and dried in a vacuum drying oven. The schematic diagram of the synthesis process is shown in Figure 1. Different volume ratios of the composite materials were used as Raman substrates for CV testing, and the result of enhancing the CV Raman spectral values was used to determine the final volume ratio between Au@Ag and Ce-UIO-66.