Enhanced SERS Detection of Formaldehyde and 4-ATP Using Metal-Organic Framework (MOF) Modified Nanomaterials

For example, Shao et al. [38] synthesized Ag/MIL-101(Cr) thin film material SERS substrates through a secondary growth method and a reduction reaction for second growth of MIL-101(Cr) thin film on a titanium sheet. The film was then immersed in a silver nitrate solution and exposed to ultraviolet light, causing the silver ions to be reduced into silver nanoparticles and attached to the MIL-101(Cr) thin film. Raman detection of the probe molecule 4-ATP revealed that it could still be detected at a concentration of 10^-11M.

Fu et al. [39] in-situ grew a porous zeolitic imidazolate framework-8 (ZIF-8) shell on gold nanostars (AuNS) to capture and alter the path of formaldehyde molecules. Compared to current SERS detection methods, this unique pore-sized core-shell AuNS@ZIF-8 nanocomposite material allows formaldehyde molecules to reach the metal surface through ZIF-8 channels. With the help of the ZIF-8 shell, AuNS@ZIF-8 exhibits extremely high sensitivity to formaldehyde molecules, with a detection limit of nearly one billionth (ppb).