Understanding the Etiology of Non-Cicatricial Alopecia: Challenges and the Use of Genetic Prediction in Mendelian Randomization

In the observational study, the determination of the etiology was limited by confounding and reverse causality, which hindered the ability to determine whether various characteristics were the cause or consequence of non-cicatricial alopecia. The use of genetic prediction in MR relies on assessing the impact of exposure levels and risks on the results.