JZ-14 Inhibits Treg Cell Differentiation in a Dose-Dependent Manner
In the Treg cell differentiation experiment, JZ-14 showed dose-dependent inhibition on Treg cell differentiation, reducing the expression of FoxP3. The IC50 values for inhibiting Treg cell differentiation in three donors were 13.65 nM, 22.27 nM, and 13.97 nM, respectively.
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