Understanding Sample Mobility in SERS Analysis: Impact on Substrate Interaction and Detection

In the given context, the mobility of the sample refers to the ability of the analyte molecules or particles to move or diffuse within the sample matrix. It indicates the extent to which the analyte can freely move or disperse in the medium. Samples with high mobility are more likely to have analyte molecules or particles distributed evenly throughout the matrix, while samples with low mobility may have analyte molecules or particles that are less dispersed and more localized in certain regions. The mobility of the sample can affect the interaction between the analyte and the SERS substrate, as well as the efficiency of analyte detection and enrichment.