Sulfapyridine Detection Mechanism: Adsorption on Au/MIL-101 (Fe)

We propose that Sulfapyridine can primarily be detected through two mechanisms. Firstly, MIL-101 (Fe) possesses numerous pores and active sites on its surface, allowing for physical adsorption of Sulfapyridine molecules. This type of adsorption is non-specific and relies on Van der Waals forces, electrostatic interactions, and hydrogen bonding. Secondly, a chemical bond can form between gold nanoparticles and Sulfapyridine molecules. Gold nanoparticles have a high electron affinity and active surface, allowing them to form gold-nitrogen bonds with the nitrogen atoms in Sulfapyridine. Additionally, the surface of gold nanoparticles contains abundant surface oxides that can form gold-oxygen bonds with the oxygen atoms in Sulfapyridine. These mechanisms work together to effectively adsorb Sulfapyridine molecules onto the Au/MIL-101 (Fe) surface.