Enhancing Bone-Implant Integration: The Role of Mechano-Chemical Coupling and Osteoimmune Modulation

| Original Text | Corrected Text | Explanation ||---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|| mineralization and osteoimmune microenvironment at the bone-implant interface are important prerequisites for osseointegration (24, 40). | mineralization and osteoimmune microenvironment at the bone-implant interface are important prerequisites for osseointegration (24, 40). | No mistake found. || were sparsely distributed on the bare Ti plate on day 7, which did | were sparsely distributed on the bare Ti plate on day 7, which did | No mistake found. || not increase by day 14 (Fig. 6A). | not increase by day 14 (Fig. 6A). | No mistake found. || that the surplus of peripheral phosphoric groups on PA-Zn@TiNPs | that the surplus of peripheral phosphoric groups on PA-Zn@TiNPs | No mistake found. || served as reactors that were conducive to ion-to-ion interactions. | served as reactors that were conducive to ion-to-ion interactions. | No mistake found. || that PA-Zn@TiNPs had the potential to promote M1-to-M2 transition (41). | that PA-Zn@TiNPs had the potential to promote M1-to-M2 transition (41). | No mistake found. || were upregulated in PA-Zn@TiNPs plate than in materials (Fig. 6G). | were upregulated in PA-Zn@TiNPs plate than in other materials (Fig. 6G). | Added 'other' before 'materials' for clarity. || that PA-Zn@TiNPs promoted M2 macrophage transition to create an osteogenic microenvironment for BMSCs, resulting in quick and intensive osteogenesis. | that PA-Zn@TiNPs promoted M2 macrophage transition to create an osteogenic microenvironment for BMSCs, resulting in quick and intensive osteogenesis. | No mistake found. || alveoli showed no obvious tissue damage, suggesting good biocompatibility of CaO2/PA-Zn@TiNPs in vivo (fig. S16). | alveoli and showed no obvious tissue damage, suggesting good biocompatibility of CaO2/PA-Zn@TiNPs in vivo (fig. S16). | Added 'and' before 'showed' for better sentence structure. || turnover and a favorable osteogenic immune milieu contributed to the boosted osseointegration surrounding the developed CaO2/PA-Zn@TiNPs. | turnover and a favorable osteogenic immune milieu contributed to the boosted osseointegration surrounding the developed CaO2/PA-Zn@TiNPs. | No mistake found. |