Sepsis-induced Immunosuppression: Cellular Dysfunctions, Immunotherapy, and Future Directions

This article discusses sepsis-induced immunosuppression, covering aspects from cellular dysfunctions to immunotherapy. It highlights how sepsis disrupts the immune system, leading to excessive inflammation and immune suppression. The author presents current treatment methods for sepsis-induced immunosuppression, including immune enhancers and immunomodulators, while also acknowledging their limitations and challenges. The article concludes by emphasizing the need for further research to understand the mechanisms of sepsis-induced immunosuppression and develop more effective immunotherapy strategies to improve sepsis patient survival and treatment outcomes.