Improving Scientific Expression: Gene Enrichment Analysis in Nature Style

To conduct our enrichment analyses and visualizations, we employed the clusterProfiler package. Specifically, we utilized this tool to perform Gene Ontology (GO), Kyoto Gene and Gene Encyclopedia (KEGG), and Gene Set Enrichment Analysis (GSEA) on our dataset. Notably, GSEA was performed on all genes within the dataset. We then identified the key genes of IHF by intersecting the differentially expressed genes (DEGs) with the important module genes of the Weighted Gene Co-expression Network Analysis (WGCNA). Subsequently, we conducted GO and KEGG enrichment analyses on these key genes of IHF.