急性脑梗死发病机制最新研究及参考文献

急性脑梗死的发病机制是多因素交织的，包括缺血、缺氧、脑水肿、炎症反应等。最新研究表明，急性脑梗死的发病机制与神经元凋亡、神经元再生、胶质细胞激活、自噬、线粒体功能障碍等有关。

'参考文献：'

1. Yang Y, Rosenberg GA. Blood-brain barrier breakdown in acute and chronic cerebrovascular disease. Stroke. 2011;42(11 Suppl): S332-6.

2. Chen H, Li Y, Li T, et al. The role of inflammation in stroke. Frontiers in Neurology. 2019;10: 1168.

3. Zhao H, Wang J, Gao L, et al. Mitochondrial dynamics regulates ischemic neuronal injury in vitro and in vivo. Aging and Disease. 2019;10(3): 582-99.

4. Li Y, Qi Y, Huang TH, et al. Neural stem cell transplantation promotes stroke recovery via the PAR-1/FGFR1 signaling pathway. Brain Research. 2020;1729: 146623.

5. Liu X, Liu J, Zhao S, et al. Autophagy in cerebral ischemia and its therapeutic implications. Journal of Molecular Medicine. 2020;98(11): 1469-83.