Reversed Phase-Liquid Chromatography (RP-HPLC) for Recombinant AAV Genome Integrity Assessment
Reversed Phase-Liquid Chromatography (RP-HPLC) is a powerful analytical technique used to assess the genome integrity of recombinant adeno-associated virus (rAAV) vectors. This method separates AAV capsids containing the desired full-length genome from those with truncated genomes or other impurities, providing critical information about the quality and efficacy of the gene therapy product.
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