The correct option is C. Right extramedullary and intradural lesions.

The symptoms and physical examination findings suggest that John is experiencing a spinal cord injury. The fact that the muscle strength of the right lower limb is grade 2 with increased muscle tension and hyperreflexic tendon reflex indicates that there is a lesion affecting the spinal cord. The absence of pain and temperature sense, motion sense, and vibration sense, as well as the positive Babinski sign on the right side, further supports this diagnosis.

The auxiliary examination of incomplete obstruction of spinal canal by lumbar puncture and cerebrospinal fluid protein 0.65gL indicates that there is a lesion in the spinal canal. The fact that the lesion is transverse means that it is affecting a specific area of the spinal cord.

Option A (Right intramedullary lesion) and B (Left intramedullary lesion) are incorrect because they suggest that the lesion is inside the spinal cord (intramedullary), which does not match with the symptoms of increased muscle tension and hyperreflexic tendon reflex.

Option D (Left extramedullary and intradural lesions) is incorrect because the symptoms and physical examination findings suggest that the lesion is affecting the right side of the body, not the left.

Option E (Left extradural lesion) is incorrect because the symptoms indicate that the lesion is affecting the spinal cord itself, not just the outer layer (dura mater) of the spinal cord.

Therefore, the correct option is C (Right extramedullary and intradural lesions) because it best matches the symptoms and auxiliary examination findings.

Right Extramedullary and Intradural Lesions: A Case Study of Spinal Cord Injury

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