As mentioned earlier, exploring the entire molecular space based on physics alone is practically impossible due to its size (Figure~\ref{fig:2222}) \cite{Chuang2022,COLEY2021133,Lipinski2004nature,Kang2018}. In the construction of GIBAC, a hybrid approach combining AI and physics is used. However, AI algorithms still struggle to predict intermolecular binding data that are different from the training data set, which only covers a limited portion of the molecular space \cite{Kang2018}. To address this, synthetic data and its generators, such as Chen et al. \cite{Chen2021Synthetic,Jadon2023}, are utilized.

Can you rewrite the following lLaTeX-format texts such that it becomes more concise and simple and elegantAs discussed above the size of the entire molecular space makes an exhaustive physics-based ex

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