How IMMU-132 affect TROP2 expression in molecular aspectsheip me find some famous articles concerning IMMU-132

One famous article concerning IMMU-132 and its effect on TROP2 expression is:

1. "IMMU-132, an anti-Trop-2 antibody-drug conjugate, shows activity in patients with refractory, metastatic triple-negative breast cancer" by Bardia A, et al. (2017). This article discusses the clinical trial results of IMMU-132 in patients with triple-negative breast cancer, highlighting its efficacy in targeting TROP2-expressing tumors.

Other notable articles on this topic include:

2. "TROP2: A novel prognostic marker in squamous cell carcinoma of the oral cavity" by Wang J, et al. (2016). This study investigates the expression of TROP2 in oral squamous cell carcinoma and its correlation with patient prognosis, suggesting TROP2 as a potential therapeutic target.

3. "TROP2 expression in extramammary Paget's disease: Potential therapeutic target" by Li J, et al. (2015). This article explores the expression of TROP2 in extramammary Paget's disease and its potential as a therapeutic target, providing insights into the molecular aspects of TROP2.

4. "TROP2 overexpression promotes proliferation and invasion of ovarian cancer cells" by Zhao P, et al. (2014). This study investigates the role of TROP2 in ovarian cancer, demonstrating its involvement in promoting cell proliferation and invasion, further supporting the rationale for targeting TROP2 with IMMU-132.

These articles provide a comprehensive understanding of the molecular aspects of TROP2 expression and its relevance in various cancer types, including the potential therapeutic implications of IMMU-132.