The results of this study indicate that coffee intake and alcohol consumption have a significant causal effect on AGA, as evidenced by the IVW analysis. The IVW OR per one SD increase for coffee intake was 35.914 (95% CI, 2.522-511.354) with a P-value of 0.008, while for alcohol consumption it was 24.098 (95% CI, 1.291-449.698) with a P-value of 0.033. The MR-Egger intercept and Cochran's Q tests did not show evidence of directional pleiotropy or heterogeneity for these associations. Leave-one-out analysis and scatter plot analysis did not detect significant outliers. The weighted median and MR-Egger methods also supported the positive association, although with insignificant p-values. BMI showed a borderline significant causal effect on AGA, with an IVW OR per one SD increase of 2.097 (95% CI, 0.999-4.402) and a P-value of 0.050. However, the MR-Egger regression and weighted median methods did not yield statistically significant results. Genetically predicted waist circumference was not found to be associated with AGA risk. Other lifestyle factors, including tea intake, smoking, insomnia, television watching, computer use, and driving time, were not significantly associated with AGA. For AA, insomnia was found to have a causal effect, with an IVW OR per one SD increase of 10.301 (95% CI, 1.273-83.339) and a P-value of 0.029. No significant associations were observed between other lifestyle factors and AA

Based on the following paragraph from study results write down the discussion part:This study identified 40 41 353023113 83 7 458 and 374 SNPs from the GWAS database as IVs P 5×10-08 for coffee intak

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