中文翻译:A total of 212 883 patients achieved tumor regression with a median reduction ratio of TTV of 860 An increasing reduction ratio of TTV was associated with a gradually ascending successful convers
总共212名患者(88.3%)达到了肿瘤缩小的效果,中位病例的TTV缩小比例为86.0%。TTV缩小比例的增加与转化成功的结果逐渐升高相关。缩小比例大于86.0%的患者比缩小比例在0-86.0%或小于0的患者有更好的生存率(5年总体生存率,64.4%对44.9%对23.5%,P < 0.001;5年无进展生存率,36.3%对28.2%对6.5%,P < 0.001)。多元分析表明,TTV缩小比例≤86.0%(OR [95%CI]:4.956 [2.654–9.253],P < 0.001)是转化失败结果的独立因素。Cox分析显示,TTV缩小比例≤86.0%是不利的总体生存率(HR [95%CI]:2.216 [1.332–3.688],P = 0.002)和无进展生存率(HR [95%CI]:2.023 [1.376–2.974],P < 0.001)的独立因素。
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