Additionally, Boesch's detailed Retriever structure revealed the impact of cancer-related mutations on the formation of Commanders and the disruption of membrane protein homeostasis. This provides a crucial foundation for comprehending the biological and pathological consequences connected to Retriever-CCC-mediated endosomal recycling.

rephraseMoreover Boesch’s high-resolution structure of Retriever uncovered how cancerassociated mutations disrupted Commander formation and impaired membrane protein homeostasis provide a fundamental

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