what is naive pluripotency

Naive pluripotency refers to the state of embryonic stem cells (ESCs) or induced pluripotent stem cells (iPSCs) that are in an undifferentiated state and have the potential to give rise to all cell types in the body. Naive pluripotency is characterized by the expression of specific genes, such as Oct4 and Nanog, and the ability to form embryoid bodies in vitro. Naive pluripotent cells are considered to be more versatile and have a greater potential for therapeutic applications than their differentiated counterparts