润色：Ulceration of carotid artery plaque occurs when necrotic lipid substances are released into the bloodstream following plaque rupture resulting in a depression The minimum size of this depression is

Revised: Ulceration of carotid artery plaque occurs when necrotic lipid substances are released into the bloodstream following plaque rupture, resulting in a depression with a minimum size of approximately 1×1mm. This depression is connected to the blood and contrast agent in the lumen of the carotid artery, making it challenging for conventional ultrasound to display plaque ulcers. However, ultrasound contrast imaging can help identify them. Literature reports suggest that CEUS can provide a specificity of up to 92.6% for plaque rupture characterized by plaque ulceration. In addition, 3D ultrasound imaging technology offers a more comprehensive view of the ulceration and free-floating thrombus within the plaque