Type 2 T helper cells, or Th2 cells, are a type of white blood cell that play a critical role in the adaptive immune response. They are a subset of CD4+ T cells and are characterized by their ability to produce certain cytokines, such as interleukin-4 (IL-4), interleukin-5 (IL-5), and interleukin-13 (IL-13).

Th2 cells are primarily involved in promoting immune responses against parasitic infections, allergies, and asthma. When an individual is exposed to an allergen or a parasite, Th2 cells are activated and release cytokines that recruit and activate other immune cells, such as eosinophils and mast cells, to the site of infection or inflammation. These immune cells then work together to eliminate the pathogen or allergen.

However, dysregulation of Th2 cell responses can lead to chronic allergies, asthma, and other immune-mediated diseases. In individuals with these conditions, Th2 cells are overactive and produce excessive amounts of cytokines, leading to chronic inflammation and tissue damage.

Overall, Th2 cells play a crucial role in mediating immune responses against parasites and allergies, but their dysregulation can contribute to the development of immune-related diseases

type 2 T helper cell

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