润色：Sulfapyridine is one of the most widely used sulfonamide antibiotics which has the effect of preventing and treating animal diseases Its prevention and treatment effect is significant and its price

Revision: Sulfapyridine is a widely utilized sulfonamide antibiotic known for its effectiveness in preventing and treating animal diseases. It is not only cost-effective but also has a significant impact. However, the slow metabolism of this antibiotic in animals can lead to its accumulation, resulting in antibiotic residues in poultry meat consumed by humans. This, in turn, poses a risk to human health. In order to address this issue, China's "National Food Safety Standard for Maximum Residue Limits of Veterinary Drugs in Food" (GB 31650-2019) has established a maximum residue limit (MRL) of 0.1 mg/kg for sulfonamide drugs in animal-derived food.

Currently, the most commonly used methods for detecting sulfapyridine residues include liquid chromatography, enzyme-linked immunosorbent assay, and fluorescence detection. However, these methods are plagued by several issues such as complex pre-treatment operations, lengthy detection times, a high demand for samples, and the potential loss of samples. To overcome these challenges, surface-enhanced Raman spectroscopy offers a simple, rapid, and traceless approach to detect sulfapyridine at low concentrations