请帮我优化下面的英文:In recent years direct sample introduction techniques were developed to shorten the analysis time which mainly benefits from ambient ionization methods Ambient ionization MS allows for dire
In recent years, there have been advancements in direct sample introduction techniques aimed at reducing analysis time, primarily through the use of ambient ionization methods. Ambient ionization mass spectrometry enables the direct analysis of specimens in their natural environment, minimizing or eliminating the need for sample preparation. This approach has found applications in the rapid screening of illicit drugs and abuse drug testing.
For example, desorption electrospray ionization (DESI), which is one of the earliest ambient ionization methods developed by Cooks' team, has been employed in therapeutic drug monitoring (TDM) and the rapid detection of illicit drugs on fingerprints. Similarly, the direct analysis in real time (DART) MS technique introduced by Cody and colleagues excels in analyzing solid surfaces and is suitable for biomatrix analysis. It has been successfully used in various analyses of new psychoactive substances (NPS).
Additionally, matrix-assisted laser desorption ionization (MALDI), easy ambient sonic spray ionization (EASI), paper spray ionization (PSI), dielectric barrier discharge ionization (DBDI), low-temperature plasma ionization (LTP), and desorption atmospheric pressure photoionization (DAPPI) have been applied in drug testing strategies such as TDM and harm-reduction drug checking
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