翻译成英文：1 经组织或细胞病理学确诊的结肠癌肝转移患者；2 既往接受一线化疗经过RECIST 11评估疾病控制PR+SD的患者；3 已行根治性局部治疗手术、消融、SBRT达到NED的结直肠癌肝转移患者。NED的定义：a患者经过局部治疗以后使用CT MRI PET-CT未见原发灶和转移灶肿瘤残留征或者肿瘤活性。b对可疑病灶的穿刺未见癌细胞。4 已完成NED后的常规辅助化疗如4-8程Xelox方案、

Patients with colon cancer liver metastasis confirmed by organization or cellular pathology;
Patients who have previously received first-line chemotherapy and have achieved disease control (PR+SD) evaluated by RECIST 1.1;
Patients with colorectal cancer liver metastasis who have undergone curative local treatment (surgery, ablation, SBRT) and achieved no evidence of disease (NED). Definition of NED: a. After local treatment, no residual tumor or tumor activity is found in the primary and metastatic lesions using CT, MRI, PET-CT. b. No cancer cells are found in the biopsy of suspicious lesions.
Patients who have completed NED and have no disease progression after adjuvant chemotherapy (such as 4-8 cycles of Xelox regimen, 6-12 cycles of FOLFOX regimen, or completion of fluoropyrimidine monotherapy and no longer receiving adjuvant chemotherapy recently);
The time from the last chemotherapy to enrollment does not exceed 2 months;
Performance status (ECOG) score ≤ 2;
Age 18-75 years old (including 18 and 75 years old);
Hematology: WBC> 3 × 109 /L; PLT> 80 × 109 /L; Hb> 90g/L;
Liver function: ALT and AST ≤ 2.5 × ULN; bilirubin ≤ 1.5 × ULN
Renal function: serum creatinine ≤ 1.5 × ULN or creatinine clearance rate (CCr) ≥ 60ml/min;
Signed informed consent form, patients willing to undergo this treatment regimen, able to adhere to medication and have good compliance