brief summary：结直肠癌肝转移的流行病学结直肠癌Colorectal cancerCRC在中国是一种高发且发病率上升最快的消化道恶性肿瘤之一我国2015年结直肠癌新发病例376万人占全部癌症88死亡191万占全部癌症死亡68从2000年至2015年间年均发病人数增加87严重威胁国人的生命健康1。结直肠癌具有早期发现治疗效果好外科切除可获得治愈机会。然而远处转移是结直肠癌致死的主要原因之

Colorectal cancer (CRC) is one of the most common and rapidly increasing malignant tumors of the digestive system in China. Colorectal liver metastases (CRLM) are a major cause of death in CRC patients, with a 5-year survival rate of less than 20%. Despite curative treatment, over 60% of CRLM patients still experience recurrence. Postoperative adjuvant therapy is needed to reduce the risk of recurrence. However, traditional adjuvant chemotherapy may not completely eliminate residual tumor cells, leading