请将这段英文改写通过调整语序增减字数替换同义词等方式避免与原文出现连续3个字相同的句子使这段话更加具有逻辑符合论文的规范：Overexpression of miR-331-3p and miR-9-5p in SH-SY5Y cell line impaired autophagic activity and promoted amyloid plaques formation Moreover

Impaired autophagic activity and enhanced formation of amyloid plaques were observed in the SH-SY5Y cell line due to the overexpression of miR-331-3p and miR-9-5p. Additionally, administration of miR-331-3p and miR-9-5p antagomirs in late-stage AD mice resulted in improved cognition, mobility, and enhanced clearance of Aβ.