An increasing amount of literature indicates that miRNAs are causally associated with Alzheimer's disease (AD) through their direct influence on the underlying pathogenic pathways. This is exemplified by their ability to target the expression of APP or BACE1, thereby modifying the risk and/or progression of the disease.

请将下列语句改写避免与原文出现连续5个字相同的句子并是语言更学术化A growing body of literature suggests that miRNAs are causally linked to AD by directly affecting the underlying pathogenic pathways for example by targeting APP or BA

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