Brief summary：21 Study populationA total of 240 consecutive CRLM patients who were diagnosed withinitially unresectable CRLMs from December 2012 to January 2020 atour center were enrolled in this retr

This section provides information about the study population, image acquisition, treatment strategy, follow-up, and statistical analysis used in the study. The study included 240 consecutive patients with initially unresectable colorectal liver metastases (CRLMs) who were diagnosed between December 2012 and January 2020. The patients were of Asian ethnicity and met specific inclusion criteria. The characteristics of CRLMs were assessed using a three-dimensional reconstruction system. The treatment strategy was determined by a multidisciplinary team, and all patients received first-line chemotherapy. Tumor response was evaluated every 4 courses of chemotherapy. Follow-up was conducted through clinical visits and imaging. Statistical analysis was performed to identify risk factors associated with conversion outcome and prognosis.