The patients whose lesions were detected to have submucosal invasion deeper than 500 μm lateral andor vertical margin involvement and lymphovascular invasion were advised to undergo additional treatme

Patients with lesions exhibiting submucosal invasion deeper than 500 μm, as well as lateral and/or vertical margin involvement and lymphovascular invasion, were advised to consider undergoing additional treatment. Possible treatment options may include surgical resection, radiation therapy, or combination therapy, depending on the individual case and the patient's overall health status. It is important to discuss all treatment options and potential risks and benefits with the patient and their healthcare team before making a final decision