Silicon-Based Engineering for Enhanced D-Fructose-6-Phosphate Hydrolyase Activity: Computational Insights into the Enhancement Mechanism

This study investigates the application of silicon-based engineering approaches to boost the activity of D-fructose-6-phosphate hydrolyase. Computational analysis delves into the mechanism by which this enhancement occurs, providing valuable insights into the potential of silicon-based engineering for optimizing enzyme efficiency. The research explores the structural modifications introduced by silicon-based engineering and their impact on enzyme activity. Computational simulations and molecular dynamics studies are employed to analyze the interactions between the enzyme and substrate, revealing the key factors contributing to enhanced catalytic efficiency. The findings contribute to the understanding of enzyme engineering principles and offer a promising avenue for developing novel and highly efficient biocatalysts.