what is the IC50 and Ki value of mianserin with its each target

Mianserin is a drug that has multiple targets in the body, making it difficult to provide a single IC50 or Ki value for the drug. However, here are some reported values for mianserin's activity on some of its known targets:

• Serotonin 5-HT2A receptor: IC50 = 5.6 nM, Ki = 1.8 nM
• Serotonin 5-HT2C receptor: IC50 = 2.5 nM, Ki = 0.8 nM
• Histamine H1 receptor: IC50 = 14 nM, Ki = 3.4 nM
• Adrenergic α1 receptor: IC50 = 68 nM, Ki = 21 nM
• Adrenergic α2 receptor: IC50 = 10 nM, Ki = 3.3 nM

Note that these values may vary depending on the experimental conditions and the specific assay used to measure the drug's activity