Breast cancer is currently the most extensively researched and prevalent malignancy worldwide [22]. According to the latest global cancer burden data, breast cancer accounted for 2.26 million cases in 2020 and remains the leading cause of cancer-related deaths among women globally [23]. Historically, most breast cancer patients have been treated conservatively, with endocrine therapy (ET) being a common approach. ET involves the use of hormonal or anti-hormonal drugs to modify the tumor growth environment and conditions, which ultimately inhibits tumor growth. Both selective estrogen receptor modulators (SERMs) and aromatase inhibitors have been utilized in breast cancer treatment, and ER-positive patients have shown a favorable response to endocrine therapy

帮我润色这段学术论文Breast cancer is currently the most researched malignancy and the most common cancer in the world 22 The latest global cancer burden data estimates 226 million cases of breast cancer in 2020

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