1. In Figure 5G, the authors clearly exaggerate their research findings. Based on the existing data, it's difficult to be convinced of their emphasis on the role of HSD11B1 in regulating DC differentiation in ESC and iDC cells.

  2. The title of the article is confusing and it's unclear what it intends to convey.

Mild concerns:

  1. In multiple instances in the figures, the authors fail to provide a description of biological replicates for the samples, which raises doubts about the statistical analysis of the data presented in the figures.
  2. The article lacks clarity in describing the experimental methods and presenting the data results in several instances.
Critical Evaluation of Research Findings: Concerns Regarding Methodology and Interpretation

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