Drug R&D Failure Rate: 90-95% Success?

The failure rate of drug research and development (R&D) is quite high. According to various estimates, the failure rate can range from 90% to 95%. This means that only around 5% to 10% of drugs that enter clinical trials ultimately receive regulatory approval and make it to the market. The high failure rate is primarily attributed to factors such as efficacy issues, safety concerns, and a lack of overall effectiveness during clinical trials. Additionally, the complex and lengthy process of drug development, which can take several years and involve significant investments, further contributes to the high failure rate.