Integrated amplified aptasensor with in-situ precise preparation of copper nanoclusters for ultrasensitive electrochemical detection of microRNA的创新点

The development of an integrated amplified aptasensor that combines target amplification and detection in a single step, reducing analysis time and increasing sensitivity.

The in-situ precise preparation of copper nanoclusters on the aptasensor surface for signal amplification, resulting in ultrasensitive detection of microRNA.

The use of aptamers as the recognition element, which offers high selectivity and sensitivity towards target microRNA molecules.

The employment of a simple and cost-effective electrochemical detection method, which enables real-time monitoring and quantitative analysis of microRNA.

The potential application of this aptasensor in clinical diagnosis and disease monitoring due to its high sensitivity and specificity