Thank you for your feedback. Based on your suggestion, we have reduced the use of acronyms in the manuscript. While we have retained OPD and RF, we have replaced other acronyms, such as OT for optimum treatment, with their full names.

请润色下面这句话:Thanks for your comments As per your suggestion we have minimized the usage of acronyms in the manuscript The OPD and RF are remained however other acronyms including OT for optimum treatment

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