PTL以时间和浓度依赖性的方式抑制细胞增殖在医学SCI期刊论文中有哪些英语表述？

"PTL inhibits cell proliferation in a time- and concentration-dependent manner."
"Cell growth was suppressed by PTL in a dose- and time-dependent manner."
"The inhibitory effect of PTL on cell proliferation was found to be both concentration- and time-dependent."
"PTL exerted its anti-proliferative effect in a time- and concentration-dependent fashion."
"The anti-proliferative effect of PTL was observed in a concentration- and time-dependent manner."

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