Directed Evolution of a Selective and Sensitive Serotonin Sensor via Machine Learning这篇文章中通过荧光素酶建立了机器学习方法更为适度的修饰配体结合口袋配对上这句什么意思

This sentence means that in the article "Directed Evolution of a Selective and Sensitive Serotonin Sensor via Machine Learning," a machine learning method was established using a fluorescent enzyme, and the ligand/binding pocket pairing was more moderately modified to improve the selectivity and sensitivity of the serotonin sensor.