Use a more scientific expression translate these sentences：随后他们还发现17LamD内酯环上的羰基、C-8位和C-20位的羟基分别能能与Topo I 结合口袋中的3个重要结合位点Arg 364 Asn 722 Glu 356 产生相互作用形成三元复合物。

Subsequently, they also discovered that the carbonyl group on the lactone ring, as well as the hydroxyl groups at C-8 and C-20 on LamD, can interact with the three important binding sites (Arg 364, Asn 722, Glu 356) in the binding pocket of Topo I to form a ternary complex.