急性脑梗死早期神经功能恶化的定义及其最新参考文献
急性脑梗死早期神经功能恶化的定义是指患者在发病后24小时内出现神经功能恶化，包括脑功能缺损、认知障碍、肢体运动功能障碍等。
最新参考文献：
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Kim BJ, Han MK, Park TH, et al. Prediction of progressive motor deficits in acute ischemic stroke. J Stroke. 2014;16(1):53-60.
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Ma H, Campbell BCV, Parsons MW, et al. Thrombolysis guided by perfusion imaging up to 9 hours after onset of stroke. N Engl J Med. 2019;380(19):1795-1803.
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Kim BJ, Han MK, Park TH, et al. Early neurological deterioration in acute stroke patients: a multicenter study. J Stroke. 2016;18(2):238-246.
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Lee MJ, Chung JW, Ahn MJ, et al. Prediction of early neurologic deterioration using multimodal magnetic resonance imaging in acute ischemic stroke. Stroke. 2015;46(2):373-378.
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