use scientific tone to revise Genetics imaging and clinical diseases are intrinsically linked Genetics exerts a pivotal influence on the pathogenesis of numerous clinical disorders while imaging modal

The disciplines of genetics, imaging, and clinical diseases are inextricably intertwined. Genetics plays a critical role in the pathogenesis of a multitude of clinical disorders, while imaging modalities facilitate their diagnosis and monitoring. Recent advancements in genetic testing have enabled the more precise identification of hereditary disorders that may present with clinical symptoms. Imaging techniques, such as magnetic resonance imaging (MRI) and computed tomography (CT), provide indispensable insights into the anatomical and functional alterations associated with various genetic maladies. The integration of genetic data with clinical and imaging information empowers the design of tailored therapeutic approaches for patients afflicted with genetic diseases. Figure 3 succinctly summarizes the interrelationships among imaging modalities, genetics loci, and clinical diseases.