The detection mechanism of SiQDs-(K/L-P)ox and (K/L-P)ox was investigated in Figure 4a. ONOO- is a potent biological oxidant that can directly oxidize polypeptides and react with hydroxylation and nitrification of aromatic compounds such as tyrosine. The main fluorescence of SiQDs-(K/L-P)ox and (K/L-P)ox materials arises from the oxidized tripeptide and L-Phe moiety in melanin. Upon addition of ONOO-, the oxidation reaction at the imide group breaks the peptide bond, generating an unconjugated molecular group and leading to a loss of fluorescence. The possible reaction mechanism of SiQDs-(K/L-P)ox is presented in Figure S8. In Figure 4c, the color of (K/L-P)ox solution changed from red to yellow, and the fluorescence intensity decreased from strong to weak after the oxidation reaction, indicating that the bond break relieved the conjugation effect of the group, resulting in lighter color. Chromatography testing of SiQDs-(K/L-P)ox was conducted in Figure 4b, revealing that the spots before the reaction were clearly visible, and no spots were observed at the same position after the reaction, confirming that the addition of ONOO- led to the dissociation of the SiQDs-(K/L-P)ox and validating the detection mechanism.

Please help me to polish this technical paper to make it read more smooth and reasonable Then the detection mechanism of SiQDs-KL-Pox and KL-Pox was explored in Figure 4a ONOO- is a strong oxidizing

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