Please help me to polish this technical paper to make it read more smooth and reasonable:Melanin-like fluorophores in aqueous solution are closely related to their interactions with water molecules wh
Melanin-like fluorophores in aqueous solutions are intricately linked to their interactions with water molecules, which can lead to energy transfer from the excited state of the fluorophore to the surrounding water. To mitigate intermolecular interactions, steric hindrance can be employed. The addition of sulfonic acid groups can result in (K/P)ox being in a hydrophobic environment, which reduces the nonradiative energy transfer from the excited state to the surrounding water. For instance, Sun et al.33 developed a novel type of NIR-II probe, FD-1080 J-aggregates, whose luminescence intensity was enhanced by the addition of 1, 4-butane sultone. Although the luminescence intensity is improved, the large particle size of melanopsin typically results in severe photobleaching, impeding long-term imaging in vitro and in vivo, and making it unsuitable for biomedical applications. II-VI semiconductor QDs have the advantages of size-tunable emission color, strong fluorescence, and high resistance to photobleaching. However, semiconductor QDs with excellent optical properties lack the ability to specifically detect ONOO-. As a result, we are inspired to develop a new semiconductor QDs with melanin-like characteristics.
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