The tumor microenvironment (TME) is a complex entity characterized by immune cells, stromal cells, blood vessels, and extracellular matrix. The development of dynamic and collaborative relationships between cancer cells and TME components that support cancer cell survival, local invasion, and metastasis has been observed. For example, TME controls a program that promotes blood vessel formation to ensure nutrient supply and waste clearance, and immune cells in TME can assist with tumor immune escape, among other functions [1].

请把下列语句用不同的英文语句表示出来意思不变:肿瘤微环境tumor microenvironment TME是一个复杂的实体其标志性特征包括免疫细胞、基质细胞、血管和细胞外基质。癌细胞与支持癌细胞存活、局部侵袭和转移播散的TME成分之间发展出了动态协作的关系。例如TME控制着一个促进血管生成的程序以保障营养供应和清除代谢废物TME中的免疫细胞可以协助肿瘤免疫逃逸等1。

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