Tumor-associated changes in glycans are notable for their increased branching of N-glycans, higher density of O-glycans, and production of truncated versions of normal counterparts (Tn, sTn, and T antigens). Additionally, unusual forms of terminal structures containing sialic acid and fucose (sLea and sLex epitopes) are generated due to the genetic and epigenetic desregulation of glycogenes and the tumor microenvironment.

请将下列英文换一种语句表述方式Significantly tumor-associated glycan changes comprise increased branching of N-glycans higher density of O-glycans generation of truncated versions of normal counterparts Tn sTn and T

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