Based on the above observations we proposed a general SV caller method-SVcnn which can accurately call DELs INSs and INVs The reason why we didnt add the function of detecting DUPs to SVcnn is that we

Overall, SVcnn is a promising SV caller method that can accurately detect DELs, INSs, and INVs. Its reliance on a simple CNN and ability to handle multi-allelic SVs make it a valuable addition to the current SV calling toolbox. However, its inability to directly detect DUPs may be a limitation in some cases, although this can be overcome by comparing INS sequences to the reference. The improved F1-score and reduced false SVs make SVcnn an attractive option for SV detection, particularly in cases where read depth is greater than 5x.