Decidualization is a process where cells in the uterus transform into secretory cells. It is important for successful embryo implantation and placenta formation. Abnormal decidualization can cause infertility. Our study focuses on understanding how the antioxidant system mediated by SLC7A11 helps protect against oxidative stress during decidualization. We found that the pentose phosphate pathway is crucial for this process, providing the necessary components for antioxidant synthesis. Inhibiting this pathway impairs decidualization. Targeting antioxidant synthesis or supplementing the pathway may be a potential treatment for infertility related to impaired decidualization

请将如下内容简化成不超过100字的英文:Decidualization is the differentiation process whereby fibroblast-like endometrial stromal cells transform into secretory-like decidual cells Normal decidualization is essential fo

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