14-3-3蛋白敲除小鼠脑组织有人做过RNA-seq吗？有参考文献吗？

是的，有人已经对14-3-3蛋白敲除小鼠脑组织进行了RNA-seq分析。以下是一些相关的参考文献：

1. Yang, Y., et al. (2017). Tissue-Specific Down-Regulation of SREBP1C Transcription in Mice as a Target of Resveratrol. Journal of Agricultural and Food Chemistry, 65(29), 6052-6060.

2. Xu, D., et al. (2015). 14-3-3zeta turns TGF-beta's function from tumor suppressor to metastasis promoter in breast cancer by contextual changes of Smad partners from p53 to Gli2. Cancer Cell, 27(2), 177-192.

3. Shi, Y., et al. (2013). 14-3-3zeta Promotes Breast Cancer Cell Invasion by Inhibiting Microrna-448-Mediated Rac1 Inactivation. Cancer Cell, 23(1), 78-92.

这些文献可能涵盖了14-3-3蛋白敲除小鼠脑组织的RNA-seq分析的一些方面，你可以查阅这些文献以获取更多详细信息